\u5305\u8863\u6750\u6599\u5bf9\u5305\u8863\u5de5\u827a\u53ca\u5305\u8863\u7247\u8d28\u91cf\u7684\u5f71\u54cd\u7814\u7a76<\/strong><\/a><\/p>\n\u6211\u4eec\u5236\u5242\u7814\u53d1\u4eba\u5458\u5728\u8584\u819c\u5305\u8863\u8fc7\u7a0b\u4e2d\u65f6\u5e38\u4f1a\u9047\u5230\u5404\u79cd\u95ee\u9898\uff1a\u6bd4\u5982\u8584\u819c\u5305\u8863\u6750\u6599\u4e0e\u7247\u82af\u7684\u76f8\u5bb9\u6027\u95ee\u9898\uff0c\u6216\u8005\u5305\u8863\u5de5\u5e8f\u653e\u5927\u8fc7\u7a0b\u4e2d\u5e38\u9047\u5230\u7684\u7c98\u7247\u3001\u7834\u76ae\u3001\u6a58\u76ae\u3001\u5f00\u88c2\u7b49\u95ee\u9898\u3002\u9047\u5230\u8fd9\u4e9b\u95ee\u9898\u6709\u65f6\u5019\u4f1a\u4e0d\u77e5\u6240\u63aa\uff0c\u5c24\u5176\u5bf9\u4e8e\u4e00\u4e2a\u65b0\u624b\u6765\u8bf4\u3002\u6240\u4ee5\u7b14\u8005\u89c9\u5f97\uff0c\u60f3\u8981\u5305\u597d\u8863\uff0c\u9996\u5148\u8981\u5148\u5bf9\u5305\u8863\u6750\u6599\u7684\u914d\u65b9\u7ec4\u6210\u5177\u5907\u4e00\u5b9a\u7684\u4e86\u89e3\uff0c\u5728\u6b64\u57fa\u7840\u4e0a\uff0c\u57fa\u4e8e\u5305\u8863\u6750\u6599\u7684\u7279\u70b9\uff08\u6bd4\u5982\u4e0d\u540c\u7684\u6210\u819c\u6750\u6599\u6240\u5177\u5907\u7684\u4f73\u6210\u819c\u6e29\u5ea6\u6709\u6240\u4e0d\u540c\uff09\u624d\u80fd\u505a\u51fa\u5305\u8863\u53c2\u6570\u7684\u5408\u7406\u4f18\u5316\uff0c\u63d0\u9ad8\u4ea7\u54c1\u7684\u5305\u8863\u6548\u7387\u3002<\/p>\n
<\/p>\n
\u6211\u4eec\u5e38\u7528\u7684\u5305\u8863\u6750\u6599\u4e00\u822c\u662f\u5361\u4e50\u5eb7\u7684\u6b27\u5df4\u4ee3\u7cfb\u5217\uff0c\u5728\u5361\u4e50\u5eb7\u7684\u5b98\u7f51\u4e0a\u53ef\u4ee5\u770b\u5230\u6b27\u5df4\u4ee3\u4ea7\u54c1\u7684\u5347\u7ea7\u8fc7\u7a0b\uff0c\u5176\u4e3b\u8981\u662f\u56f4\u7ed5\u6210\u819c\u6750\u6599\u6765\u7684\uff0c\u4e00\u4ee3\u5305\u8863\u7c89\u662f\u4ee5\u5355\u4e00\u805a\u5408\u7269HPMC\u4e3a\u6210\u819c\u6750\u6599\u7684\uff0c\u6bd4\u5982\u6211\u4eec\u5e38\u7528\u7684Y-1-7000\u578b\u53f7\uff1b\u4e8c\u4ee3\u662f\u4ee5\u5355\u4e00\u805a\u5408\u7269PVA\u4e3a\u6210\u819c\u6750\u6599\u7684\u54c1\u79cd\uff0c\u5982\u6211\u4eec\u5e38\u7528\u768485G68918\u578b\u53f7\u3002\u5728\u6b64\u57fa\u7840\u4e0a\u53c8\u9010\u6e10\u884d\u751f\u4e86\u4e24\u79cd\u6216\u591a\u79cd\u805a\u5408\u7269\u7684\u5171\u7528\uff0c\u4ee5\u53ca\u8fdb\u4e00\u6b65\u5347\u7ea7\u5373\u4f7f\u7528\u590d\u5408\u805a\u5408\u7269\uff0c\u6bd4\u5982PVA-PEG\u7684\u805a\u5408\u7269\uff0c\u5b83\u62e5\u6709\u5f88\u4f4e\u7684\u6210\u819c\u6e29\u5ea6\uff0c\u56e0\u800c\u64cd\u4f5c\u6e29\u5ea6\u8303\u56f4\u4f1a\u66f4\u5bbd\u3002<\/p>\n
\u8584\u819c\u5305\u8863\u6280\u672f\u7684\u539f\u7406\u5373\u5c06\u5305\u8863\u6eb6\u6db2\u6216\u6df7\u60ac\u6db2\u4ee5\u55b7\u96fe\u7684\u65b9\u5f0f\u55b7\u5c04\u5230\u7247\u82af\u7684\u8868\u9762\uff0c\u901a\u8fc7\u63a5\u89e6\u3001\u94fa\u5c55\u3001\u6db2\u6ef4\u95f4\u7684\u76f8\u4e92\u805a\u7ed3\u4f5c\u7528\u800c\u5728\u7247\u82af\u8868\u9762\u5f62\u6210\u7684\u4e00\u5c42\u8863\u819c\u3002\u5982\u679c\u4ee5\u6210\u819c\u6750\u6599\u662f\u5426\u5728\u4ecb\u8d28\u4e2d\u6eb6\u89e3\u4e3a\u4f9d\u636e\uff0c\u5305\u8863\u6750\u6599\u53ef\u4ee5\u5206\u4e3a\u6eb6\u6db2\u578b\u548c\u5206\u6563\u578b\uff0c\u6eb6\u6db2\u578b\u5305\u8863\u6db2\u662f\u901a\u8fc7\u96fe\u5316\u3001\u63a5\u89e6\u7247\u9762\u5e76\u94fa\u5c55\u3001\u6eb6\u5242\u84b8\u53d1\u3001\u805a\u5408\u7269\u94fe\u76f8\u4e92\u6e17\u900f\uff0c\u7ecf\u5386\u51dd\u80f6\u72b6\u6001\uff0c\u7136\u540e\u8fdb\u4e00\u6b65\u5e72\u71e5\u5f62\u6210\u8584\u819c\uff1b\u800c\u5206\u6563\u578b(\u96fe\u6ef4\u5185\u6210\u819c\u6750\u6599\u662f\u6df7\u60ac\u72b6\u6001)\u5373\u901a\u8fc7\u96fe\u5316\u3001\u63a5\u89e6\u7247\u9762\u5e76\u94fa\u5c55\u3001\u6eb6\u5242\u84b8\u53d1\u3001\u4e92\u4e0d\u8fde\u63a5\u7684\u72ec\u7acb\u5206\u5b50\u8fdb\u4e00\u6b65\u52a0\u70ed\uff08\u8d85\u8fc7\u4f4e\u6210\u819c\u6e29\u5ea6\uff09\u3001\u8f6f\u5316\u3001\u6d41\u52a8\uff0c\u76f8\u4e92\u8fde\u63a5\u6210\u819c\u3002<\/p>\n
\u8584\u819c\u5305\u8863\u6750\u6599\u4e00\u822c\u662f\u7531\u6210\u819c\u5242\u3001\u589e\u5851\u5242\u3001\u6297\u7c98\u5242\u548c\u7740\u8272\u5242\u56db\u90e8\u5206\u7ec4\u6210\uff1a<\/p>\n
1\uff09\u6210\u819c\u6750\u6599<\/p>\n
\u8584\u819c\u5305\u8863\u914d\u65b9\u4e2d\u5e38\u7528\u7684\u6210\u819c\u6750\u6599\u5305\u62ec\uff1a\u7f9f\u4e19\u57fa\u7532\u57fa\u7ea4\u7ef4\u7d20\u3001\u7f9f\u4e19\u57fa\u7ea4\u7ef4\u7d20\u3001\u805a\u4e59\u70ef\u9187\u3001\u4e19\u70ef\u9178\u6811\u8102\u7c7b\u3001\u805a\u4e59\u70ef\u5421\u54af\u70f7\u916e\u7b49\u3002\u5176\u4e2d\uff0cHPMC\u5728\u8584\u819c\u5305\u8863\u914d\u65b9\u4e2d\u5e94\u7528\u4e3a\u5e7f\u6cdb\uff0c\u4f46\u662f\u548c\u5176\u4ed6\u6210\u819c\u6750\u6599\u5982PVA\u76f8\u6bd4\uff0c\u56e0\u4e3a\u5e38\u89c4\u5206\u5b50\u7ea7\u7684HPMC\u5728\u6c34\u6027\u8584\u819c\u5305\u8863\u6eb6\u6db2\u4e2d\u7c98\u6027\u66f4\u5927\uff0c\u8fd9\u4e00\u7279\u6027\u9650\u5236\u4e86\u5176\u5728\u4e00\u4e9b\u9ad8\u56fa\u542b\u91cf\u7247\u5242\u5305\u8863\u914d\u65b9\u4e2d\u7684\u5e94\u7528\uff0c\u4f8b\u5982\u7b14\u8005\u6240\u8d1f\u8d23\u7684\u9879\u76ee\u5f00\u59cb\u4f7f\u7528\u7684\u5305\u8863\u6750\u6599\u5c31\u662f\u6b27\u5df4\u4ee3Y-1-7000\uff0c\u5176\u4e3b\u8981\u6210\u5206\u662fHPMC 5cp, \u56fa\u542b\u91cf\u4e00\u822c\u662f\u572812%\u7684\u6c34\u5e73\uff0c\u5305\u8863\u6548\u7387\u76f8\u5bf9\u6bd4\u8f83\u4f4e\u3002\u968f\u7740\u5305\u8863\u6750\u6599\u5382\u5bb6\u8fdb\u884c\u914d\u65b9\u7684\u4e0d\u65ad\u4f18\u5316\uff0c\u5728\u4f18\u5316\u7684\u914d\u65b9\u4e2d\u4e00\u822c\u90fd\u4f1a\u540c\u65f6\u4f7f\u7528\u51e0\u79cd\u89c4\u683c\uff0c\u7efc\u5408\u5229\u7528\u5176\u4e0d\u540c\u7684\u7269\u7406\u6027\u80fd\uff0c\u6b64\u5916\uff0c\u53ef\u80fd\u8fd8\u4f1a\u5728\u5176\u4e2d\u52a0\u5165\u4e00\u4e9b\u522b\u7684\u8f85\u6599\uff0c\u4f7f\u5f97\u4f18\u5316\u540e\u7684\u914d\u65b9\u56fa\u542b\u91cf\u53ef\u63d0\u9ad8\u81f320%\u6216\u4ee5\u4e0a\uff0c\u6781\u5927\u7684\u63d0\u9ad8\u4e86\u5305\u8863\u6027\u80fd\u53ca\u5305\u8863\u6548\u7387\u3002\u00a0 \u00a0 \u00a0 \u00a0\u00a0<\/p>\n
\u4f8b\u5982\u6709\u6587\u732e\u7814\u7a76\uff1a\u539f\u4f4e\u5206\u5b50\u91cfHPMC\uff08hypromellose 2906, VLV\uff09\u7684\u8584\u819c\u5305\u8863\u914d\u65b9\uff0c\u56e0\u8be5\u79cd\u805a\u5408\u7269\u8584\u819c\u673a\u68b0\u5f3a\u5ea6\u8f83\u5f31\uff0c\u4f1a\u5bfc\u81f4\u8584\u819c\u5305\u8863\u7247\u7684\u7a33\u5b9a\u6027\u95ee\u9898\uff0c\u800c\u5728\u8be5\u914d\u65b9\u4e2d\uff0c\u6dfb\u52a0\u5c11\u91cf5 wt%\u5e38\u89c4\u7684HPMC\uff083.35 wt% HPMC E50\u548c1.65 wt% HPMC E3)\u65f6\uff0c\u4f18\u5316\u540e\u7684\u5305\u8863\u914d\u65b9\u53ef\u663e\u8457\u63d0\u9ad8\u5305\u8863\u819c\u7684\u97e7\u6027\u4ece\u800c\u63d0\u9ad8\u7247\u5242\u7684\u8d2e\u5b58\u7a33\u5b9a\u6027\u548c\u8d28\u91cf\uff0c\u540c\u65f6\u4e5f\u5927\u9650\u5ea6\u5730\u4fdd\u6301\u4e86\u9ad8\u6548\u7684\u5305\u8863\u5de5\u827a\u548c\u6e29\u548c\u7684\u5305\u8863\u6761\u4ef6\uff0c\u5927\u7a0b\u5ea6\u7684\u89c4\u907f\u4e86\u201c\u7c98\u7247\u201d\u98ce\u9669\u95ee\u9898\u3002<\/p>\n
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<\/p>\n
2\uff09\u589e\u5851\u5242<\/p>\n
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3\uff09\u6297\u7c98\u5242<\/p>\n
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<\/p>\n
4\uff09\u7740\u8272\u5242<\/p>\n
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5\uff09\u5176\u4ed6\u6dfb\u52a0\u5242<\/p>\n
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