{"id":4112,"date":"2024-07-22T15:12:31","date_gmt":"2024-07-22T07:12:31","guid":{"rendered":"\/\/www.30-onna.com\/?p=4112"},"modified":"2024-07-22T15:15:39","modified_gmt":"2024-07-22T07:15:39","slug":"%e7%be%b0%e5%9f%ba%e5%8c%96%e5%81%b6%e8%81%94%e5%8f%8d%e5%ba%94-carbonylative-cross-coupling","status":"publish","type":"post","link":"\/\/www.30-onna.com\/archives\/4112","title":{"rendered":"\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94 Carbonylative Cross Coupling"},"content":{"rendered":"<p><a href=\"\/\/www.30-onna.com\/\" target=\"_self\" rel=\"noopener\"><strong>\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94<\/strong><\/a>Carbonylative Cross Coupling<\/p>\n<p>\u5229\u7528\u4e00\u6c27\u5316\u78b3\u80fd\u63d2\u5165\u78b3-\u91d1\u5c5e\u952e\u8fd9\u4e00\u7279\u6027\uff0c\u5728\u5076\u8054\u53cd\u5e94\u4e2d\u540c\u65f6\u5f15\u5165\u7fb0\u57fa\uff0c\u751f\u6210\u916f\uff0c\u9170\u80fa\uff0c\u916e\uff0c\u9187\u7b49\u4ea7\u7269\u3002\u5728\u6709\u673a\u5408\u6210\u4e2d\u662f\u4e00\u4e2a\u975e\u5e38\u6709\u6548\u7387\u7684\u53cd\u5e94\u3002\u5e38\u7528\u4e8e\u94af\u50ac\u5316\u5076\u8054\u53cd\u5e94\u3002<\/p>\n<p>\u6211\u4eec\u77e5\u9053\u4e00\u6c27\u5316\u78b3\u5f88\u5bb9\u6613\u63d2\u5165\u78b3-\u91d1\u5c5e\u952e\u4e4b\u95f4\u3002\u7528\u94af\u50ac\u5316\u5242\uff0c\u6709\u57fa\u5364\u5316\u7269\uff0c\u4e00\u6c27\u5316\u78b3\uff0c\u9187\u4e00\u8d77\u53cd\u5e94\u4f1a\u751f\u6210\u916f\u3002\u7528\u80fa\u4ee3\u66ff\u5176\u4e2d\u7684\u9187\u4f1a\u5f97\u5230\u9170\u80fa\uff0c\u7528\u6c22\u6e90\u66ff\u4ee3\u9187\u4f1a\u5f97\u5230\u919b\uff0c\u6362\u6210\u6709\u673a\u91d1\u5c5e\u8bd5\u5242\u5c31\u4f1a\u5f97\u5230\u916e\u3002<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4113\" src=\"\/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1700901272895-1.png\" width=\"429\" height=\"431\" srcset=\"\/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1700901272895-1.png 429w, \/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1700901272895-1-348x350.png 348w, \/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1700901272895-1-200x200.png 200w, \/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1700901272895-1-300x300.png 300w, \/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1700901272895-1-220x221.png 220w\" sizes=\"(max-width: 429px) 100vw, 429px\" title=\"\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94 Carbonylative Cross Coupling\u63d2\u56fe\" alt=\"\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94 Carbonylative Cross Coupling\u63d2\u56fe\" \/><\/p>\n<p>\u63d2\u7fb0\u53cd\u5e94\u5236\u5907\u7fa7\u9178\u53ca\u5176\u884d\u751f\u7269\u5b9e\u4f8b<\/p>\n<p>\u63d2\u7fb0\u53cd\u5e94\u5236\u5907\u919b<\/p>\n<p>\u63d2\u7fb0\uff01\u9009\u62e9\u6027\u5408\u6210\u919b\u548c\u9178<\/p>\n<p>Saegusa\u6c27\u5316\u53cd\u5e94<\/p>\n<p>1978\u5e74\uff0cT. Saegusa\u8bfe\u9898\u7ec4\u62a5\u9053\u4e86\u5728\u4e59\u8148\u4e2d\u7845\u57fa\u70ef\u9187\u919a\u548c\u4e9a\u5316\u5b66\u8ba1\u91cf\u7684Pd(OAc)2\u548c\u5bf9\u82ef\u918c\u5ba4\u6e29\u4e0b\u53cd\u5e94\u5f97\u5230\u76f8\u5e94\u7684\u03b1,\u03b2-\u7fb0\u57fa\u5316\u5408\u7269\u3002\u916e\u8f6c\u5316\u4e3a\u76f8\u5e94\u7684\u70ef\u9187\u57fa\u7845\u70f7\uff0c\u5728\u94af\u50ac\u5316\u4e0b\u5c06\u5176\u533a\u57df\u9009\u62e9\u6027\u6c27\u5316\u4e3a\u03b1\uff0c\u03b2-\u4e0d\u9971\u548c\u916e\u7684\u53cd\u5e94\u88ab\u79f0\u4e3aSaegusa\u6c27\u5316\u53cd\u5e94\u3002<\/p>\n<p>Wacker\u6c27\u5316\u53cd\u5e94<\/p>\n<p>\u6c2f\u5316\u94af\u548c\u6c2f\u5316\u94dc\u50ac\u5316\u4e0b\u70ef\u70c3\u6c27\u5316\u5f97\u5230\u916e\u7684\u53cd\u5e94\uff0c\u5c11\u6570\u60c5\u51b5\u4e0b\u53ef\u4ee5\u6c27\u5316\u4e3a\u919b\u3002Image<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4114\" src=\"\/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1715824610771.png\" width=\"567\" height=\"307\" srcset=\"\/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1715824610771.png 567w, \/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1715824610771-350x190.png 350w, \/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1715824610771-220x119.png 220w\" sizes=\"(max-width: 567px) 100vw, 567px\" title=\"\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94 Carbonylative Cross Coupling\u63d2\u56fe1\" alt=\"\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94 Carbonylative Cross Coupling\u63d2\u56fe1\" \/><\/p>\n<p>Fukuyama\u5076\u8054\u53cd\u5e94<\/p>\n<p>\u6709\u673a\u950c\u5316\u5408\u7269\u548c\u786b\u4ee3\u9178\u916f\u5728\u94af\u50ac\u5316\u5242\u4e0b\u5076\u8054\u5f97\u5230\u916e\u7684\u53cd\u5e94\u3002\u6b64\u53cd\u5e94\u662fTohru Fukuyama\u57281998\u5e74\u53d1\u73b0\u3010Tetrahedron Letters. 39 (20): 3189\u20133192\u3011\uff0c\u662f\u6700\u65b0\u53d1\u73b0\u7684\u7ecf\u5178\u94af\u50ac\u5316\u5076\u8054\u53cd\u5e94\u3002\u6b64\u53cd\u5e94\u5316\u5b66\u9009\u62e9\u6027\u9ad8\uff0c\u53cd\u5e94\u6761\u4ef6\u6e29\u548c\uff0c\u6240\u7528\u8bd5\u5242\u4f4e\u6bd2\u3002\u7531\u4e8e\u6709\u673a\u950c\u8bd5\u5242\u53cd\u5e94\u6d3b\u6027\u8f83\u4f4e\uff0c\u6240\u4ee5\u6b64\u53cd\u5e94\u6709\u5f88\u597d\u7684\u5b98\u80fd\u56e2\u8010\u53d7\u5ea6\uff0c\u916e\uff0c\u916f\uff0c\u786b\u919a\uff0c\u82b3\u57fa\u6eb4\uff0c\u82b3\u57fa\u6c2f\u548c\u919b\u7b49\u6b64\u53cd\u5e94\u6761\u4ef6\u4e0b\u90fd\u53ef\u4ee5\u7a33\u5b9a\u5b58\u5728\u3002<\/p>\n<p>Fukuyama\u8fd8\u539f\u53cd\u5e94<\/p>\n<p>Pd\/C\u50ac\u5316\u4e0b\u5229\u7528\u4e09\u4e59\u57fa\u7845\u70f7\u8fd8\u539f\u786b\u4ee3\u9178\u916f\u751f\u6210\u919b\u7684\u53cd\u5e94\u3002<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-4115\" src=\"\/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1698331978756-1.jpg\" width=\"300\" height=\"225\" srcset=\"\/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1698331978756-1.jpg 300w, \/\/www.30-onna.com\/wp-content\/uploads\/2024\/07\/1698331978756-1-220x165.jpg 220w\" sizes=\"(max-width: 300px) 100vw, 300px\" title=\"\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94 Carbonylative Cross Coupling\u63d2\u56fe2\" alt=\"\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94 Carbonylative Cross Coupling\u63d2\u56fe2\" \/><\/p>\n<p>Fujiwara-Moritani Reaction(\u85e4\u539f-\u5b88\u8c37\u53cd\u5e94)<\/p>\n<p>Pd\u50ac\u5316\u5242\u5b58\u5728\u4e0b\uff0c\u5bf9\u65e0\u4fee\u9970\u7684\u82ef\u73af\u8fdb\u884c\u7684\u76f4\u63a5\u7684\u70ef\u70c3\u5316\u5076\u8054\u53cd\u5e94\u3002\u4e5f\u662f\u50ac\u5316C-H\u6d3b\u5316\u7684\u4e00\u4e2a\u4f8b\u5b50\u3002\u53cd\u5e94\u5f62\u5f0f\u57fa\u672c\u4e0eHeck\u53cd\u5e94\u76f8\u5f53\u3002<\/p>\n<p>\u94af\u50ac\u5316\u7684Hiyama\u5076\u8054\u53cd\u5e94\u793a\u4f8b\uff0c\u6867\u5c71\u5076\u8054\u53cd\u5e94\uff08Hiyama Cross Coupling\uff09<\/p>\n<p>\u94af\u50ac\u5316\u4e0b\u6709\u673a\u7845\u8bd5\u5242\u548c\u6709\u673a\u5364\u4ee3\u7269\u6216\u4e09\u6c1f\u7532\u78fa\u9178\u916f\u8fdb\u884c\u4ea4\u53c9\u5076\u8054\u7684\u53cd\u5e94\u3002\u53cd\u5e94\u4e2d\u5e38\u5e38\u52a0\u5165\u4e00\u79cd\u6c1f\u5316\u7269\uff08TASF\u3001TBAF\uff09\u6216\u78b1\uff08\u5982\u6c22\u6c27\u5316\u94a0\u3001\u78b3\u9178\u94a0\uff09\u7684\u6d3b\u5316\u8bd5\u5242\uff0c\u5426\u5219\u53cd\u5e94\u4f1a\u5f88\u96be\u8fdb\u884c\u3002\u50ac\u5316\u5faa\u73af\u548cKumada\u5076\u8054\u7c7b\u4f3c\u3002<\/p>\n<p>\u7845\u4e0a\u7684\u53d6\u4ee3\u57fa\u901a\u5e38\u5fc5\u987b\u662f\u6742\u539f\u5b50\u6216\u8005\u82ef\u57fa\u3002\u5982\u679c\u662f\u4e09\u70f7\u57fa\u7532\u7845\u70f7\uff0c\u5219\u96be\u4ee5\u5f62\u6210\u7845\u9178\u76d0\u4e2d\u95f4\u4f53\uff0c\u6240\u4ee5\u5076\u8054\u53cd\u5e94\u8f83\u96be\u8fdb\u884c\u3002\u7845\u5177\u6709\u4f4e\u6bd2\u6027\u7684\u4f18\u70b9\uff0c\u662f\u4e00\u4e2a\u5f88\u6709\u6f5c\u529b\u7684\u53cd\u5e94\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7fb0\u57fa\u5316\u5076\u8054\u53cd\u5e94Carbonylative Cross Coupling \u5229\u7528\u4e00\u6c27\u5316\u78b3\u80fd\u63d2\u5165\u78b3-\u91d1\u5c5e\u952e\u8fd9\u4e00\u7279\u6027\uff0c\u5728\u5076\u8054\u53cd\u5e94\u4e2d\u540c\u65f6\u5f15\u5165\u7fb0\u57fa\uff0c\u751f\u6210\u916f\uff0c\u9170\u80fa\uff0c\u916e\uff0c\u9187\u7b49\u4ea7\u7269\u3002\u5728\u6709\u673a\u5408\u6210\u4e2d\u662f\u4e00\u4e2a\u975e\u5e38\u6709\u6548\u7387\u7684\u53cd\u5e94\u3002&#8230; <\/p>\n","protected":false},"author":2,"featured_media":4113,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45],"tags":[],"_links":{"self":[{"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/posts\/4112"}],"collection":[{"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/comments?post=4112"}],"version-history":[{"count":1,"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/posts\/4112\/revisions"}],"predecessor-version":[{"id":4116,"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/posts\/4112\/revisions\/4116"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/media\/4113"}],"wp:attachment":[{"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/media?parent=4112"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/categories?post=4112"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.30-onna.com\/wp-json\/wp\/v2\/tags?post=4112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}